PROBLEM TO BE SOLVED: To provide an extract of Perilla frutescens var. crispa f. viridis. that is excellent in functions of enhancing the activity of in vivo antioxidation system and of increasing the expression of antioxidant enzyme, and to provide production methods for obtaining the same.SOLUTION: An extract of Perilla frutescens var. crispa f. viridis. having an antioxidant function which activates Nrf2-ARE pathway is obtained by a subcritical process using Perilla frutescens var. crispa f. viridis. as a raw material and using water as an extraction solvent, at the temperature of 140 to 230°C, under the pressure equal to or more than the saturation vapor pressure at each temperature. A production method of the extract having an antioxidant function that activates Nrf2-ARE pathway, comprises a subcritical process of performing the subcritical process.SELECTED DRAWING: Figure 1
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