PARTHENOLIDE FREE BIOACTIVE INGREDIENTS FROM FEVERFEW (TANACETUM PARTHENIUM) AND PROCESSES FOR THEIR PRODUCTION

摘要

PROBLEM TO BE SOLVED: To provide bioactive ingredients that include isolated bioactive fractions derived from cell juice of fresh biomass of a feverfew (Tanacetum parthenium) plant.SOLUTION: Any portions of a feverfew plant may be included, including e.g., a leaf, flower, shoot, stem, and root thereof. The fresh biomass is processed under conditions effective to yield a cell juice supernatant and a membrane fraction. The cell juice supernatant is treated under conditions effective to yield a first cell juice serum supernatant and a cytoplasm fraction precipitate. The cytoplasm fraction precipitate is then isolated as a fractional component that is substantially free of α-unsaturated γ-lactones, particularly, that is substantially free of parthenolide. A bioactive fraction also has anti-inflammatory and antioxidant activity.SELECTED DRAWING: None