首页> 外国专利> METHODS FOR DIAGNOSING ONCOLOGICAL DISORDERS USING EPIMETABOLIC SHIFTERS, MULTIDIMENSIONAL INTRACELLULAR MOLECULES OR ENVIRONMENTAL INFLUENCERS

METHODS FOR DIAGNOSING ONCOLOGICAL DISORDERS USING EPIMETABOLIC SHIFTERS, MULTIDIMENSIONAL INTRACELLULAR MOLECULES OR ENVIRONMENTAL INFLUENCERS

机译:利用表皮移位剂,多维细胞内分子或环境影响因子诊断肿瘤性疾病的方法

摘要

PROBLEM TO BE SOLVED: To provide methods and formulations for diagnosing oncological disorders in humans using epimetabolic shifters, multidimensional intracellular molecules or environmental influencers.;SOLUTION: The invention provides a method for assessing the efficacy of a therapy for treating an oncological disorder in a subject. The method includes comparing the level of expression of a marker present in a first sample obtained from the subject before at least a portion of the treatment regimen is administered to the subject, the marker being selected from specific markers, and the level of expression of the marker present in a second sample obtained from the subject after at least a portion of the treatment regimen is administered to the subject, wherein a modulation in the level of expression of the marker in the second sample as compared to the first sample is an indication that the therapy is efficacious for treating the oncological disorder in the subject.;SELECTED DRAWING: Figure 1;COPYRIGHT: (C)2017,JPO&INPIT
机译:解决的问题:提供使用表观代谢移位剂,多维细胞内分子或环境影响因子诊断人的肿瘤疾病的方法和制剂。 。该方法包括在将至少一部分治疗方案施用于受试者之前,比较存在于从受试者获得的第一样品中的标志物的表达水平,该标志物选自特定标志物,以及该标志物的表达水平。在将治疗方案的至少一部分施用于受试者之后,存在于从受试者获得的第二样品中的标志物,其中与第一样品相比,第二样品中标志物的表达水平的调节表明该疗法对治疗该受试者的肿瘤疾病有效。;部分图纸:图1;版权所有:(C)2017,JPO&INPIT

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