COMBINATIONS OF SOLIFENACIN AND SALIVARY STIMULANTS FOR THE TREATMENT OF OVERACTIVE BLADDER

摘要

PROBLEM TO BE SOLVED: To provide combinations of agents used for reducing dry mouth, a side effect of a sustained release formulation of solifenacin or a pharmaceutically acceptable salt thereof used for the treatment of overactive bladder.SOLUTION: The combinations are characterized by administering a therapeutically effective amount of a muscarinic agonist, e.g. pilocarpine 1.5-2 hours after the administration of a therapeutically effective amount of solifenacin or a pharmaceutically acceptable salt thereof.SELECTED DRAWING: None