Liver protection method and hepatoprotectant

摘要

An object of the present invention is to provide a method for protecting the liver comprising administering an extract of inflamed tissue inoculated with vaccinia virus to a patient in need of treatment, a hepatoprotective agent containing the extract as an active ingredient, and the like. In the present invention, it is recognized that administration of inflammatory tissue inoculated with vaccinia virus inhibits or suppresses hepatocyte NF-κB activation, NF-κB target gene expression, JNK activation, apoptosis and fat accumulation. It was. A preparation containing this extract as an active ingredient is a highly safe drug with few side effects. Therefore, the present invention provides a very useful method for protecting the liver and a hepatoprotectant.