Method for screening oral immunological tolerance substance and oral immunological tolerance enhancing composition using Foxp3 positive regulatory T cell and IFN- producing IL-10 producing T cell induction as an index

摘要

PROBLEM TO BE SOLVED: To provide a new screening method of an oral immunological tolerance enhancing substance and a composition containing the oral immunological tolerance enhancing substance.SOLUTION: The present invention relates to the screening method of the oral immunological tolerance enhancing substance that comprises a step of evaluating a test substance, which induces Foxp3 positive control T-cell related to immunosuppression and IFN- producing IL-10 producing T-cell, is the oral immunological tolerance enhancing substance. The present invention also relates to the oral immunological tolerance enhancing substance containing an ingredient in a soybean milk fermentation product produced by lactic acid bacterium as an active ingredient.