METHOD FOR ASSISTING DIAGNOSIS OF EFFECTIVENESS OF METHOTREXATE IN RHEUMATOID ARTHRITIS PATIENT

摘要

PROBLEM TO BE SOLVED: To provide a method for assisting diagnosis of effectiveness of MTX in a rheumatoid arthritis patient by using a novel marker set of single base polymorphism (SNP) related to effectiveness of methotrexate (MTX).SOLUTION: At least one of SNPs of at least one gene selected from FPGS gene, GGH gene and SLC19A1 gene, at least one of the SNPs of FMO2 gene, at least one of the SNPs of SLC28A3 gene, at least one of the SNPs of EPHX1 gene, and at least one of the SNPs of PPARG gene in a biological sample obtained from a rheumatoid arthritis patient are analyzed, and effectiveness of MTX in the patient is determined based on an analysis result.SELECTED DRAWING: None