The present invention provides a sample analysis device, an analysis system, an anomaly detection device and an anomaly detection method which can carry out the quality control without needing a quality control sample and a normal sample. The sample analysis device selects the measurement results of the detected persons having a certain diseases from the measurement results obtained from the sample analysis device, and the measurement results deviating from a certain burst value exclusion range are excluded out of the measurement results used for the anomaly detection, and only the measurement results in the burst value exclusion range are used as the measurement results for the anomaly detection. When the number of the measurement results used for the anomaly detection reaches a certain value, the sample analysis device calculates the average value of the measurement values of the measured items having smaller change than health, and compares the average value with a certain management range to thereby carry out the anomaly detection.
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