Adapted and targeted control of ion groups to improve the effective dynamic range of mass analyzers

摘要

A method of mass spectrometry is disclosed wherein one or more relatively abundant or intense species of ions in a first population of ions are selectively attenuated so as to form a second population of ions. The total ion current of the second population of ions is then adjusted so that the ion current corresponding to ions which are onwardly transmitted to a mass analyzer comprising an ion detector is within the dynamic range of the ion detector.