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Topical formulation composition containing a silicone-based excipient for delivering an active ingredient to a substrate

机译:包含用于将活性成分递送至基质的基于硅氧烷的赋形剂的局部制剂组合物

摘要

The present disclosure relates to a semi-solid topical drug delivery formulation including a silicone-based excipient, at least one volatile solvent, at least one active configured to be topically delivered through a patient's skin for an intended therapeutic application, and at least one enhancer. The formulation may additionally optionally include at least one agent that provides occlusivity when the formulation is applied onto a patient's skin. The at least one active may be a healthcare and/or pharmaceutical active.
机译:本公开涉及一种半固体局部药物递送制剂,其包括基于硅氧烷的赋形剂,至少一种挥发性溶剂,被配置为通过患者皮肤局部递送以用于预期治疗应用的至少一种活性剂,以及至少一种增强剂。 。所述制剂可以另外任选地包括当将所述制剂施用于患者皮肤上时提供咬合性的至少一种试剂。所述至少一种活性物质可以是保健和/或药物活性物质。

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