Respiratory medicine

摘要

A therapeutic and / or prophylactic agent for respiratory diseases, or a therapeutic and / or prophylactic agent for diseases mediated by sodium channels is provided. A drug containing a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: Ar1, Ar2: heteroaryl group, aryl group; R1, R2, R3: hydrogen atom, halogen atom, C1 -C6 alkyl group, halogenated C1-C6 alkyl group, hydroxy C1-C6 alkyl group, C1-C6 alkoxy C1-C6 alkyl group or C3-C7 cycloalkyl group, cyano group; R4, R5: hydrogen atom, halogen atom, C1-C6 alkyl group, halogenated C1-C6 alkyl group, hydroxyl group, hydroxy C1-C6 alkyl group, C1-C6 alkoxy C1-C6 alkyl group, C3-C7 cycloalkyl group, C1-C6 alkoxy group; from n: 1 An integer of 3; a heteroaryl group and an aryl group are a halogen atom, a C1-C6 alkyl group, a halogenated group 1-C6 alkyl group, hydroxyl group, hydroxy C1-C6 alkyl group, C1-C6 alkoxy C1-C6 alkyl group, C3-C7 cycloalkyl group, carboxyl group, cyano group, amino group, C1-C3 alkylamino group, di-C1 It may have a group 1 or 2 independently selected from -C3 alkylamino groups, and in the case of 2, it may be the same or different.