Method and system for controlling tuning factor with a sensor that replaces a closed-loop controller in an artificial pancreas

摘要

A system for diabetes management comprising an infusion pump, a glucose sensor and a controller is described and illustrated along with a method programmed into the controller. The infusion pump is configured to deliver insulin. The glucose sensor senses a glucose value in the subject and provides an output signal representative of the glucose value in the subject. The controller is programmed to receive a signal from at least one of a glucose sensor and a pump, and model prediction based on the subject's desired glucose value, the amount of insulin delivered, and the measured glucose value A feedback controller utilizing the control is configured to signal the pump to deliver a determined amount of insulin. The controller also delivers insulin using the tuning factor (R) for the model predictive controller in the microcontroller as a conservative setting, or the system will have a current tuning factor (R) for the controller. Configured to maintain.