Provided is a method for producing an endoderm cell in which endoderm cells can be derived from dispersed pluripotent cells and the efficiency of producing endoderm cells is improved. The method for producing an endoderm cell of the present invention is a method for producing an endoderm cell by inducing an endoderm cell from a pluripotent cell, wherein the endoderm cell inducer is An induction step of inducing pluripotent cells into the endoderm cells, and in the induction step, the cell density of the pluripotent cells at the start of induction is 0.5 × 10 4 to 2 × 10 4 cells / Cm 2 is preferable.
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机译:本发明提供一种内胚层细胞的制造方法,其中,内胚层细胞可以来自分散的多能细胞,并且可以提高内胚层细胞的生产效率。本发明的内胚层细胞的制备方法是通过从多能细胞诱导内胚层细胞来制备内胚层细胞的方法,其中所述内胚层细胞诱导剂是将多潜能细胞诱导到内胚层细胞中的诱导步骤。诱导步骤中,诱导开始时多能细胞的细胞密度优选为0.5×10 4至2×10 4细胞/ Cm 2。
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