Use of tumor necrosis factor receptor related factor 7 as a biomarker of systemic lupus erythematosus, method and kit for detecting a person suffering from systemic lupus erythematosus

摘要

A use of tumor necrosis factor (TNF) receptor-associated factor 7 (TRAF7) as a biomarker for systemic lupus erythematosus (SLE) and a method and a kit for detecting human with SLE are provided. The kit for detecting human with SLE includes TRAF7 and anti-TRAF7 antibodies. The method for detecting human with SLE includes the following steps. A plasma sample is taken from a patient with suspected SLE. The ratio of TRAF7 to total protein in the plasma sample of the patient is compared with that in the plasma sample of normal people. If the ratio of TRAF7 to total protein in the plasma sample of the patient is higher than that of the normal people, then it is possible that the patient is suffering from SLE. TRAF7 can be used as a biomarker for SLE patients in active phase and with renal involvement.