首页>
外国专利>
Disintegrating particle composition produced by a two-stage wet granulation process and orally disintegrating tablet containing the composition
Disintegrating particle composition produced by a two-stage wet granulation process and orally disintegrating tablet containing the composition
展开▼
机译:通过两步湿法制粒法制得的崩解颗粒组合物和含有该组合物的口腔崩解片
展开▼
页面导航
摘要
著录项
摘要
The objective of this invention is providing the disintegrating particle composition which can be used for the orally disintegrating tablet which has the outstanding tablet hardness and disintegrating property, its manufacturing method, etc. The present invention includes a disintegrating property comprising a first disintegrant component comprising a disintegrant having a sedimentation volume of 4.0 cm 3 / g or more with respect to water, a second disintegrant component other than the first disintegrant, and an excipient. A method for producing a particle composition, the first wet granulation step using any two of the three components, the granulated product obtained in the first wet granulation step, and the first of the three components The production method, the produced collapsible particle composition, and the collapsible particles comprising a second wet granulation step using at least one remaining component not used in the wet granulation step The present invention relates to an orally disintegrating tablet containing a composition and medicinal ingredients.
展开▼