Posterior silk gland gene expression unit and transgenic silkworm having the same

摘要

A rear silk gland gene expression unit capable of expressing recombinant peptides, particularly water-soluble peptides, in a large amount in rear silk glands of silkworms including silkworm, and gene expression units thereof and gene recombinant silkworms To be provided. A promoter of a gene encoding a protein specifically expressed in the posterior silk gland, a signal peptide derived from a protein specifically expressed in the middle silk gland functionally coupled downstream of the promoter, and a constitution of a fibroin linked downstream thereof A posterior silk gland gene expression unit comprising DNA encoding a peptide of interest not containing a protein secreted as a component.