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Method for identifying strain of M. tuberculosis and method for detecting gene mutation

机译:结核分枝杆菌菌株的鉴定方法和基因突变的检测方法

摘要

To provide a method of identifying a strain and detecting a gene mutation by using gene sequence information of M. tuberculosis etc. in a sample.SOLUTION: A consensus genome comprising a plurality of M. tuberculosis strains and analogous strains thereof is constructed, gene sequence information of strains in a sample is obtained, and the strain is identified by comparing with the consensus genome , Gene mutation of the strain can also be detected. A consensus genome can be constructed by correcting the inversion in the gene of the tuberculosis strain and its analogous strain.Selection drawing None
机译:提供一种利用样品中结核分枝杆菌等的基因序列信息鉴定菌株并检测基因突变的方法。解决方案:构建包含多个结核分枝杆菌菌株及其类似菌株的共有基因组,基因序列获得样品中的菌株信息,并通过与共有基因组比较来鉴定菌株,还可以检测该菌株的基因突变。可以通过纠正结核病菌株及其类似菌株基因的反向转化来构建共有基因组。

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