A system-level simulation includes generating netlist information including component library information, which describes instances of the hardware components, and component instance information, which describes component dynamic libraries that include models of hardware components. The simulation is generated at simulation run-time based on the netlist information. Component dynamic libraries corresponding to the component library information are loaded based on the component library information. A simulation dynamic library referenced by the component dynamic libraries is loaded. One or more interlibrary adapters corresponding to the component dynamic libraries are loaded to provide compatibility between the component dynamic libraries and an application binary interface of the simulation dynamic library. Instances of hardware components are instantiated based on the component instance information, and the instantiated instances of the hardware components are connected to form the simulation. The simulation is performed at simulation run-time responsive to the simulation being generated.
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