USING ULTRASOUND SHEAR-WAVES TO ENHANCE SKIN PERMEABILITY

摘要

Described embodiments include a system, method, and apparatus. A system includes an extracellular-fluid collection device configured to be positioned at a location on a skin of a mammal. In an embodiment, the mammal includes a live human. The system includes an ultrasonic wave transmitter configured to emit ultrasonic shear waves directable at the location. The ultrasonic shear waves have a frequency or amplitude selected to increase a permeability of the skin of the mammal to an extracellular-fluid. In an embodiment, the system includes a sensor configured to determine a rate or amount of extracellular-fluid collected by the extracellular-fluid collection device. In an embodiment, the system includes a fluid collection controller configured to regulate a parameter of ultrasonic shear waves transmitted by the ultrasonic wave transmitter in response to a determined rate or amount of fluid collected by the extracellular-fluid collection device.