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PHYSIOLOGICALLY RESPONSIVE MECHANICALLY ADAPTIVE POLYMER OPTICAL FIBERS, PRODUCTION AND METHODS OF USE
PHYSIOLOGICALLY RESPONSIVE MECHANICALLY ADAPTIVE POLYMER OPTICAL FIBERS, PRODUCTION AND METHODS OF USE
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机译:具有生理响应性的机械适应性聚合物光纤,生产方法和使用方法
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摘要
Physiologically responsive mechanically adaptive optical fibers that are suitable for optical interfacing with living organisms. The optical fibers are particularly suited for applications in optogenetics. Dry, stiff fibers display a desirable tensile storage modulus and can be readily inserted into biological and in particular cortical tissue. Exposure to conditions encountered in vivo results in reduction, often a drastic reduction in modulus. When coupled with a suitable light source, the construction can be utilized to stimulate neurons in vivo. Methods for producing and utilizing the optical fibers and devices including the optical fibers are disclosed.
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