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METHOD FOR OBTAINING A COMPOSITE COATING ON TITANIUM IMPLANTS FOR TISSUE ENGINEERING

机译:在组织工程用钛合金植入物上获得复合涂层的方法

摘要

A composite coating and method for preparing the composite coating on titanium implants for tissue culture and tissue engineering is provided. The implants are characterized in that the titanium component to be coated is placed in a aqueous solution containing calcium cations, phosphate anions, and dispersed carbon nanoparticles (such as single layer graphene oxide or graphene oxide) in an amount of about 0.05%-1.50% by weight relative to the total weight of aqueous solution. The dimensions of the dispersed graphene oxide should be around, but not limited to, 300-800 nm (X-Y), while their thickness is about 0.7-1.2 nm. The aqueous solution with carbon nanoparticles is prepared by mixing for at least 72 h in temperature in range 20-35° C. and sonicated before electrodeposition process. In the prepared solution is further placed titanium which acts as cathode element (may be the implant), and anode which can be, for example, a platinum rod. Between the cathode and anode is set a potential from −1.3V to −1.7V which results in coating formation by electrodeposition. The titanium implant before the electrodeposition process is treated in sodium hydroxide of HF to improve coating formation and thickness.
机译:提供了一种用于组织培养和组织工程的钛植入物上的复合涂层和制备该复合涂层的方法。植入物的特征在于将要涂覆的钛组分放置在水溶液中,该水溶液包含约0.05%-1.50%的钙阳离子,磷酸根阴离子和分散的碳纳米颗粒(例如单层氧化石墨烯或氧化石墨烯)重量相对于水溶液的总重量。分散的氧化石墨烯的尺寸应该是但不限于300-800nm(X-Y),而它们的厚度是大约0.7-1.2nm。通过在电沉积过程之前在20-35℃的温度下混合至少72小时并超声处理来制备具有碳纳米颗粒的水溶液。在制备的溶液中进一步放置用作阴极元素(可能是植入物)的钛和可以是例如铂棒的阳极。在阴极和阳极之间设置一个从-1.3V到-1.7V的电势,该电势导致通过电沉积形成涂层。在电沉积过程之前,将钛植入物在HF的氢氧化钠中处理,以改善涂层的形成和厚度。

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