Modified Fc Gamma Receptor Type III (FcgammaIII, HNA-1) Polypeptides and The Uses Thereof

摘要

The invention is directed to engineered Fc gamma receptor type III (Fcγ111, HNA-1) polypeptides and use of these polypeptides to detect antibodies specific for human neutrophil antigens (HNA). The invention is also directed to methods for the diagnosing and determining susceptibility for developing Transfusion Reaction Acute Lung (TRALI).