Mechanisms are provided for implementing a personalized patient care plan (PPCP) system. The PPCP system obtains personal and medical information about a patient of interest and generates a patient registry record in a patient registry based on the obtained personal and medical information. The patient registry comprises a plurality of patient registry records corresponding to a plurality of patients. The PPCP system performs a historical analysis of at least one patient registry record to identify elements of one or more personal care plans which were able to be successfully achieved by at least one corresponding patient. The PPCP system generates a personalized patient care plan for the patient of interest, comprising a sequence of patient actions to be performed by the patient of interest, based on an analysis of the obtained personal and medical information in the patient registry record and results of the historical analysis.
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