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SILK-BASED SCAFFOLD PLATFORM FOR ENGINEERING TISSUE CONSTRUCTS
SILK-BASED SCAFFOLD PLATFORM FOR ENGINEERING TISSUE CONSTRUCTS
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机译:基于丝绸的工程组织构造脚手架平台
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摘要
The inventions provided herein relate to silk-based scaffolds and methods of producing the same, which can be used for a range of tissue engineering applications. The fabrication methods described herein provide a versatile platform to incorporate hollow conduits (e.g., for nutrient/oxygen delivery) through three-dimensional silk-based scaffolds that have tunable bulk properties (e.g., but not limited to, porosity, mechanical, degradation rate) and allow endothelialization and/or cell compartmentalization, for engineering a variety of complex tissue equivalents.
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