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Treatment of sodium channel, voltage-gated, alpha subunit (SCNA) related diseases by inhibition of natural antisense transcript to SCNA

机译:通过抑制SCNA的天然反义转录本来治疗钠通道,电压门控,α亚基(SCNA)相关疾病

摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sodium channel, voltage-gated, alpha subunit (SCNA), in particular, by targeting natural antisense polynucleotides of Sodium channel, voltage-gated, alpha subunit (SCNA). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SCNA.
机译:本发明涉及反义寡核苷酸,其调节钠通道,电压门控,α亚基(SCNA)的表达和/或功能,特别是通过靶向钠通道,电压门控,α亚基(SCNA)的天然反义多核苷酸)。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与SCNA表达有关的疾病和病症中的用途。

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