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Crystal form of regadenoson and preparation method thereof

机译:瑞格狄森的晶型及其制备方法

摘要

The present invention relates to the field of medicinal chemistry, and discloses a new crystal form of regadenoson, i.e., a crystal form E of regadenoson, as well as a method for preparing the new crystal form of regadenoson. The crystal form E of regadenoson according to the present invention has excellent performances in terms of radionuclide myocardial perfusion imaging, and has a poor toxicity, good storage stability, and can be used in the preparation of a medicament used as a stress agent for radionuclide myocardial perfusion imaging.
机译:本发明涉及药物化学领域,并公开了一种新的regadenoson晶型,即regadenoson的晶型E,以及制备该regadenoson的新晶型的方法。根据本发明的regadenoson的晶型E在放射性核素心肌灌注成像方面具有优异的性能,并且具有差的毒性,良好的储存稳定性,并且可以用于制备用作放射性核素心肌的应激剂的药物。灌注成像。

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