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Peptide-hydrogel composite

机译:肽-水凝胶复合物

摘要

The present invention relates to polymers, especially polymers useful as hydrogels, and to use of hydrogels for repair or restoration of tissue. In particular, the polymers and hydrogels of the present invention can be used for the repair or restoration of cartilage, especially articular cartilage. The polymers comprise at least a monomer for binding water, a monomer for imparting mechanical properties and a monomer for binding to an extracellular protein. The hydrogels comprise a polymer comprising at least a monomer for binding water and a monomer for binding to an extracellular protein. Crosslinking polymers by binding of said extra-cellular matrix protein forms hydrogels.
机译:本发明涉及聚合物,特别是用作水凝胶的聚合物,并涉及水凝胶在组织修复或恢复中的用途。特别地,本发明的聚合物和水凝胶可用于修复或恢复软骨,特别是关节软骨。所述聚合物至少包括用于结合水的单体,用于赋予机械性能的单体和用于结合细胞外蛋白的单体。水凝胶包含至少包含用于结合水的单体和用于结合至细胞外蛋白的单体的聚合物。通过结合所述细胞外基质蛋白而交联聚合物形成水凝胶。

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