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Treating androgen decline in aging male (ADAM)-associated conditions with SARMs

机译:用SARMs治疗老年男性(ADAM)相关疾病中的雄激素下降

摘要

This invention provides methods for treatment and inhibition of a male subject having an Androgen Decline in Aging Male (ADAM)-associated condition, for example sexual dysfunction, decreased sexual libido, erectile dysfunction, hypogonadism, sarcopenia, osteopenia, osteoporosis, an alteration in cognition and mood, depression, anemia, hair loss, obesity, muscle loss, dry eye, memory loss, benign prostate hyperplasia and/or prostate cancer, by administering to the subject a selective androgen receptor modulator (SARM) compound and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, pro-drug, polymorph, crystal, or any combination thereof.
机译:本发明提供了用于治疗和抑制在雄性衰老(ADAM)相关疾病中具有雄激素下降的男性受试者的方法,例如性功能障碍,性欲降低,勃起功能障碍,性腺功能减退,肌肉减少症,骨质减少,骨质疏松症,认知改变通过向受试者施用选择性雄激素受体调节剂(SARM)化合物和/或其类似物,以及情绪,抑郁,贫血,脱发,肥胖,肌肉损失,干眼症,记忆力减退,良性前列腺增生和/或前列腺癌,衍生物,异构体,代谢产物,药学上可接受的盐,药物产品,水合物,N-氧化物,前药,多晶型物,晶体或其任意组合。

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