Benzimidazole derivatives as selective blockers of persistent sodium current

摘要

The present invention is directed to a compound of Formula I; or a pharmaceutically acceptable salt thereof; wherein R, R¹, R², R³, R⁴, m, and n are as defined herein, to pharmaceutical compositions comprising said compound, and to methods of treating diseases or conditions mediated by elevated persistent sodium current, such as an ocular disorder, multiple sclerosis, seizure disorder, and chronic pain.