Complex Coordination of sertraline, method for their preparation, Pharmaceutical compositions containing same and uses in the treatment of Psychiatric Diseases

摘要

It provides a complex Coordination of sertraline, characterized by the General formula (1): (serhu2082 u209au2099u208bu2098 mxu2099) [] (1) wherein: X is an anion selected from: (i) FLUORIDE, Chloride, bromide, iodide or, preferably, chloride; (ii) an anion or SELENIDE Selenium; and (III) an anion An amino acid derivative; M is a metal selected from calcium, Magnesium, lithium, zinc, Iron, calcium,Chromium, Copper, Manganese and Vanadium; n = an integer greater than 2; M = represents the Valence Of Metal Trace element; p = represents the Valence of anion X; thus PN M 1. In a Preferred embodiment, X is selected from chlorine, Bromine, iodine, Fluorine, or, more preferably, X is chlorine.It also provides a method for the preparation of these complexes of sertraline, Pharmaceutical compositions containing same and Uses Thereof for the preparation of drugs for the treatment of Psychiatric Disorders.