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use of aromatase inhibitor for treatment of hypogonadism and related diseases

机译:芳香酶抑制剂在性腺功能减退及相关疾病的治疗中的应用

摘要

patent use: "use of aromatase inhibitor for treatment of hypogonadism and related diseases". The present invention relates to a method of increasing testosterone levels and treating hypogonadism and aromatase inhibitor-related diseases 4,4 '- [fluor- (1-h-1,2,4-triazol-1- yl) methylene] bisbenzonitrile. The present invention also relates to a method of increasing testosterone levels and treating hypogonadism and aromatase inhibitor-related diseases 4,4 '- [fluor- (1-h-1,2,4-triazol-1- il) methylene] bisbenzonitrile in a particular dosage regimen. The invention also relates to pharmaceutical compositions comprising said 4,4'- [fluor- (1-h-1,2,4-triazol-1-yl) methylene] bisbenzonitrile aromatase inhibitor, optionally in combination with other active ingredients. . furthermore, the present invention relates to kits comprising said pharmaceutical compositions together with instructions on how to administer them.
机译:专利使用:“芳香酶抑制剂在治疗性腺机能减退及相关疾病中的用途”。本发明涉及增加睾丸激素水平和治疗性腺功能减退和与芳香化酶抑制剂有关的疾病4,4′-[氟-(1-h-1,2,4-三唑-1-基)亚甲基]双苄腈的方法。本发明还涉及增加睾丸激素水平并治疗性腺功能减退和与芳香化酶抑制剂相关的疾病的4,4'-[氟-(1-h-1,2,4-三唑-1-il)亚甲基]双苄腈的方法。特定的剂量方案。本发明还涉及药物组合物,其包含所述4,4'-[氟-(1-h-1,2,4-三唑-1-基)亚甲基]双苄腈芳香酶抑制剂,任选地与其他活性成分组合。 。此外,本发明涉及包含所述药物组合物以及如何施用它们的说明书的试剂盒。

著录项

  • 公开/公告号BR112014004879A2

    专利类型

  • 公开/公告日2017-03-14

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG;

    申请/专利号BR20141104879

  • 发明设计人 ANN TAYLOR;LLOYD B. KLICKSTEIN;

    申请日2012-09-06

  • 分类号A61K9/48;A61K31/4196;A61P5/26;A61P15/08;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:42

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