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Inhibitors of the recycling of bile acid for the treatment of cholestatic liver disease pediatricians

机译:胆汁酸回收的抑制剂,用于治疗胆汁淤积性肝病的儿科医生

摘要

Summary of the recycling of bile acid inhibitors for the treatment of cholestatic liver disease pediatricians are here provided paediatric dosage forms for use in the treatment of cholestatic liver disease by administering a non systematically to an individual, The need for it.A therapeutically effective amount of the dosage form comprising an inhibitor of a transport dependent apical sodium bile acid (asbti) or a pharmacologically acceptable salt addition.These dosage forms are also provided for use in the treatment of pediatric liver disease pediatrician, for use in a decrease in the levels of bile acids and bile acids in liver, serum, for use in the treatment of pruritus, for use in the reduction of enzymes). The liver or bilirubin which comprises administration, not systematically.To an individual in need of a therapeutically effective amount of a formulation which comprises a asbti pediatrician or a pharmacologically acceptable salt addition.
机译:本文提供了胆汁酸抑制剂用于胆汁淤积性肝病治疗的儿科医师的回收概述,该药是通过非系统性地对个体给药的,用于治疗胆汁淤积性肝病的儿科剂型。剂型包含运输依赖性心尖胆汁酸(asbti)抑制剂或药理学上可接受的盐添加物。这些剂型还提供用于治疗小儿肝病的儿科医生,以降低其水平肝,血清中的胆汁酸和胆汁酸,用于治疗瘙痒症,用于减少酶)。肝或胆红素,非系统性地给药。给需要治疗有效量的制剂的个体,所述制剂包括阿斯比特儿科医生或药学上可接受的盐添加物。

著录项

  • 公开/公告号BR112014010223A8

    专利类型

  • 公开/公告日2017-06-13

    原文格式PDF

  • 申请/专利权人 LUMENA PHARMACEUTICALS INC;

    申请/专利号BR20141110223

  • 申请日2012-10-26

  • 分类号A61K31/41;A61K31/495;A61K31/4965;A61K31/4985;A61K31/5377;A61P1/16;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:35

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