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in vitro methodology to predict the in vivo absorption time of bioabsorbable polymeric devices and implants
in vitro methodology to predict the in vivo absorption time of bioabsorbable polymeric devices and implants
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机译:体外方法来预测生物可吸收聚合物装置和植入物的体内吸收时间
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摘要
patent summary: "in vitro methodology for predicting the in vivo absorption time of bioabsorbable polymeric devices and implants". The present invention relates to a novel in vitro methodology for predicting in vivo behavior, such as absorption time or mechanical strength retention of biodegradable polymer implants and medical devices. The present invention provides a novel in vitro methodology, hydrolysis profiling, for studying the degradation of absorbable polymers. Accuracy and reproducibility were established for the selected test conditions. Data from this in vitro method is correlated with in vivo absorption data, allowing the prediction of precise in vivo behaviors such as absorption times.
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