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combination therapy for the treatment of hearing and balance disorders
combination therapy for the treatment of hearing and balance disorders
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机译:联合疗法治疗听力和平衡障碍
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摘要
The present application relates to combinations of inhibitors directed at down-regulation of genes associated with hearing loss including HES1, HES5, HEY2, CDKN1B and NOTCH1, exhibiting a beneficial effect and useful in treating or attenuating hearing loss, treating balance impairment, promoting the replacement, regeneration, or protection of otic (sensory) hair cells of the inner ear, and or effecting hearing restoration/regeneration.
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