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Use of aqueous extract and polysaccharide fraction of Thuja occidentalis as anti-inflammatory agents

机译:西方金钟柏水提取物和多糖级分作为抗炎药的用途

摘要

Use of aqueous extract and polysaccharide fraction of Thuja occidentalis as anti-inflammatory agents. This patent covers the use of aqueous extract and polysaccharide fraction of Thuja occidentalis as anti-inflammatory agents, which was confirmed by performing the anti-inflammatory activity in vivo. Various methods were used to evaluate the anti-inflammatory capacity.Methodologies were used based on the methods of measurement of paw edema induced by carrageenan and different inflammatory agents, and the determination of leukocyte migration into the peritoneal cavity induced by carrageenan, using the dry extract of T. occidentalis and The fraction of polissacarideos in various concentrations of 3.0 to 30 mg / kg intraperitoneally).In all the methods, was used as a positive control, indomethacin. The results obtained are promising and have shown that the aqueous extract and the fraction of polysaccharide of T. occidentalis have good anti-inflammatory activity, therefore, have the potential to be used as active pharmaceutical inputs in the development of new pharmaceutical forms injet u00e1veis.
机译:西方金钟柏的水提取物和多糖级分作为抗炎剂的用途。该专利涵盖了金钟柏的水提取物和多糖级分作为抗炎剂的用途,这通过体内抗炎活性得到证实。各种抗炎能力的评估方法是基于测量角叉菜胶和不同炎症剂引起的爪水肿的方法,以及使用干提取物测定角叉菜胶诱导的白细胞向腹膜腔迁移的方法。浓度为3.0至30 mg / kg腹膜内的polissacarideos分数)。在所有方法中,吲哚美辛均用作阳性对照。获得的结果是有希望的,并且已经表明,西方水柏的水提取物和多糖级分具有良好的抗炎活性,因此,有潜力在新的药物形式注射剂的开发中用作活性药物投入物。 。

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