首页> 外国专利> 2 - ((4-amino-3- (3-fluoro-5-hydroxyphenyl) -1h-pyrazolo 3,4-d pyrimidin-1-yl) methyl) -3- (2- (trifluoro-methyl) derivatives ) bezyl) quinazolin-4 (3h) -one and its use as phosphoinositide 3-kinase inhibitors

2 - ((4-amino-3- (3-fluoro-5-hydroxyphenyl) -1h-pyrazolo 3,4-d pyrimidin-1-yl) methyl) -3- (2- (trifluoro-methyl) derivatives ) bezyl) quinazolin-4 (3h) -one and its use as phosphoinositide 3-kinase inhibitors

机译:2-((4-氨基-3-(3-氟-5-羟基苯基)-1h-吡唑并[3,4-d]嘧啶-1-基)甲基)-3-(2-(三氟甲基)衍生物)苄基)喹唑啉4(3h)-一及其作为磷酸肌醇3激酶抑制剂的用途

摘要

Patent Summary: "2 - ((4-Amino-3- (3-fluoro-5-hydroxyphenyl) -1h-pyrazolo [3,4-d] pyrimidin-1-yl) methyl) -3- ( 2- (trifluoro-methyl) benzyl) quinazolin-4 (3h) -one and its use as phosphoinositide 3-kinase inhibitors ". The present invention relates inter alia to a compound of formula (I) and compositions containing them and to the use of the compounds and compositions of the compounds in the treatment, for example, of inflammatory diseases, in particular inflammatory respiratory disease. The invention also relates to methods of preparing said compounds.
机译:专利摘要:“ 2-((4-氨基-3-(3-氟-5-羟基苯基)-1h-吡唑并[3,4-d]嘧啶-1-基)甲基)-3-(2-(三氟-甲基)苄基)喹唑啉-4(3h)-一及其作为磷酸肌醇3-激酶抑制剂的用途。本发明尤其涉及式(I)的化合物和包含它们的组合物,以及该化合物和该化合物的组合物在治疗例如炎性疾病,特别是炎性呼吸道疾病中的用途。本发明还涉及制备所述化合物的方法。

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