thermostable recombinant polypeptide, immunogenic composition, recombinant expression vector and use of a thermostable recombinant polypeptide

摘要

abstract "polypeptide, immunogenic composition, recombinant expression vector and method of inducing immune reaction" thermostable oligomeric recombinant polypeptides having at least one antigenic epitope of the respiratory syncytial virus (rsv) protein fusion, comprising ectodomain frsv protein, functionality excluded in the hrb region, transmembrane and cytoplasmic domains replaced by a heterologous trimerization domain and two functional multibasic furin division sites, are useful as antigenic components in immunogenic compositions useful in immunological reaction induction and immunization methods. rsv infections.