cancer patient reaction prediction methods, cancer treatment method, treatment reaction prediction kit and innovative processes, methods and uses

摘要

summary “cancer patient reaction prediction methods, cancer treatment method, treatment reaction prediction kit and innovative processes, methods and uses” this application describes a method for predicting cancer patients' reaction capacity to treatment with an mdm2 antagonist of formulas i, ii and iii as described herein, wherein said method comprises measuring mrna expression levels of at least mdm2, preferably from a four gene panel comprising mdm2, xpc, bbc3 and cdkn2a as biomarker for reaction prediction.