pyrroloquinoline quinine lithium salt crystal, method of preparation of pyrroloquinoline quinine lithium salt crystal and pharmaceutical composition

摘要

Summary Pyrroloquinoline Quinine Lithium Salt Crystal, Method of Preparation of Pyrroloquinoline Quinine Lithium Salt Crystal and Pharmaceutical Composition The present invention provides the pyrroloquinoline quinone lithium salt crystal and a method of preparing and applying it. characteristic absorption peaks appear when the diffraction angles are 6,222 ± 0,2 °, 7,379 ± 0,2 °, 7,941 ± 0,2 °, 23,631 ± 0,2 °, 24,044 ± 0,2 °, 25,497 ± 0, 2 °, 27.541 ± 0.2 °, 30.736 ± 0.2 °, and 32.306 ± 0.2 ° degrees in an x-ray powder diffraction pattern of pyrroloquinoline quinine lithium salt. Does the maximum thermal absorption value of the pyrroloquinoline quinine lithium salt crystal appear between 90? and 96? through differential scanning calorimetry. peaks appear when the infrared spectroscopy of the pyrroloquinoline quinine lithium salt crystal is at 3396.03 cm -1, 1652.70 cm -1, 1604.48 cm -1, 1500.35 cm -1, 1355.71 cm -1, 1243.86 cm -1, 1147.44 cm -1, 808.03 cm -1, 761.74 cm -1, and 570.83 cm -1. The pyrroloquinoline quinine lithium salt polymorphism can be applied to the preparation of drugs for the cure of memory impairment. 1/1