首页> 外国专利> Chimeric products with potential use as antigenic markers for diagnosis and / or recombinant vaccines against toxoplasmosis, formed by the junction of B and t epitopes of the protein love 1Gra - 7 and sag - 1 of Toxoplasma gondii

Chimeric products with potential use as antigenic markers for diagnosis and / or recombinant vaccines against toxoplasmosis, formed by the junction of B and t epitopes of the protein love 1Gra - 7 and sag - 1 of Toxoplasma gondii

机译:可能用作弓形虫病诊断和/或重组疫苗的抗原性标记物的嵌合产品,由弓形虫love love 1Gra-7和sag-1蛋白的B和t表位连接形成

摘要

Chimeric products with potential use as antigenic markers for diagnosis and / or recombinant vaccines against toxoplasmosis, formed by the junction of B and t epitopes of the protein love 1Gra - 7 and sag - 1 of Toxoplasma gondii "this invention relates to the construction of products formed by the junction of chimeric sequences containing epitopes genetically modified cellS B and t of the antigens loves 1 through 7 and sag - 1 of Toxoplasma gondii, as well as a recombinant protein encoded by the junction of these sequences.It may be expressed in various vaccine vehicles, such as plasmids and viruses genetically modified.This invention has field in biotechnology and in the pharmaceutical industry, and may be useful in immunization of mammals and as a marker for antigenic diagnostic against toxoplasmosis.
机译:嵌合产品,可能作为诊断和/或针对弓形虫的重组疫苗的抗原标记物,由弓形虫的love 1Gra-7和sag-1蛋白的B和t表位连接形成。包含由抗原决定簇的抗原决定簇SB和t组成的嵌合序列接合处形成的产物,以及刚体弓形虫的sag-1和sag-1以及由这些序列接合处编码的重组蛋白。本发明在生物技术和制药工业领域中,可用于哺乳动物的免疫接种和作为针对弓形虫病的抗原诊断的标志物。

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