首页> 外国专利> anti-vla-1 antibody, composition comprising it, nucleic acid and vector as well as in vitro methods for determining the level of vla-1 in tissue and for identifying integrin domain i inhibitor

anti-vla-1 antibody, composition comprising it, nucleic acid and vector as well as in vitro methods for determining the level of vla-1 in tissue and for identifying integrin domain i inhibitor

机译:抗vla-1抗体,包含它的组合物,核酸和载体以及确定组织中vla-1水平和鉴定整联蛋白domain i抑制剂的体外方法

摘要

"antibodies to vla-1". The present invention relates to antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immune disorders in an individual. Also included are complex crystal structures formed by vla-1 antibodies and their ligands, and vla-1 antagonists and agonists identified using the structure coordinates of these structures.
机译:“ vla-1抗体”。本发明涉及特异性结合VLA-1整联蛋白的抗体,以及使用这些抗体治疗个体免疫疾病的方法。还包括由vla-1抗体及其配体以及使用这些结构的结构坐标确定的vla-1拮抗剂和激动剂形成的复杂晶体结构。

著录项

  • 公开/公告号BRPI0209792B1

    专利类型

  • 公开/公告日2017-03-28

    原文格式PDF

  • 申请/专利号BR20020209792

  • 申请日2002-04-12

  • 分类号A61K39/395;G01N33/50;A61K49/16;A61P29;A61P37;C07H21/04;C07K16/18;C07K16/24;C07K16/28;C07K16/46;C12N;C12N1;C12N5/10;C12N5/12;C12N5/20;C12N5/22;C12N9;C12N15/07;C12N15/09;C12N15/11;C12N15/13;G01N33/15;G01N33/53;G01N33/543;G01N33/567;G01N33/577;G06F17;G06F17/30;H04N9/64;H04N13/02;H04N15;

  • 国家 BR

  • 入库时间 2022-08-21 13:39:48

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号