首页> 外国专利> u03c3u03c5u03bdu03b8u03b5u03c3u03b5u03b9u03c2u7684u836fu7269u5305u62ecNuff0duff084uff0duff082uff0du6c28u57fauff0d4uff0du03c5u03bbu03bfu03beu03c5u03c7u03bbu03c9u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bduff09- 3 -u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09-4-u4e59u6c27u57fa-1-uff084-u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09-2-u6c27u4ee3-1uff0c2-u03b4u03b9u03c5u03b4u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bdu03bau03b1u03c1u03b2u03bfu03beu03b1u03bcu03b9u03b4u03b9u03bf- 3 -

u03c3u03c5u03bdu03b8u03b5u03c3u03b5u03b9u03c2u7684u836fu7269u5305u62ecNuff0duff084uff0duff082uff0du6c28u57fauff0d4uff0du03c5u03bbu03bfu03beu03c5u03c7u03bbu03c9u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bduff09- 3 -u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09-4-u4e59u6c27u57fa-1-uff084-u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09-2-u6c27u4ee3-1uff0c2-u03b4u03b9u03c5u03b4u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bdu03bau03b1u03c1u03b2u03bfu03beu03b1u03bcu03b9u03b4u03b9u03bf- 3 -

机译：u03c3 u03c5 u03bd u03b8 u03b5 u03c3 u03b5 u03b9 u03c2 u7684 u836f u7269 u5305 u62ecN uff0d uff084 u820d uuff0d uff0d uff084 u03bf u03be u03c5 u03c7 u03bb u03c9 u03c1 u03bf u03c0 u03c5 u03c1 u03b9 u03b4 u03b9 u03bd uff09- 3- u03c6 u03b8 u03bf u03 b u03b9 u03bd u03c5 u03bb uff09-4- u4e59 u6c27 u57fa-1- uff084- u03c6 u03b8 u03bf u03c1 u03bf u03c6 u03b03 u03 u03c6 u03b03 u03-2 - u6c27 u4ee3-1 uff0c2- u03b4 u03b9 u03c5 u03b4 u03c1 u03bf u03c0 u03c5 u03c1 u03b9 u03b4 u03b03 u03 u03b4 u03b03 u03 u03 b u03bc u03b9 u03b4 u03b9 u03bf-3-

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摘要
著录项

摘要

u76d0u548cu7ed3u6676u5f62u5f0fuff0cu63edu793au4e86Nuff0duff084uff0duff082uff0du6c28u57fauff0d4uff0du03c5u03bbu03bfu03beu03c5u03c7u03bbu03c9u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bduff09- 3 -u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09-4-u4e59u6c27u57fa-1-uff084-u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09uff0d2uff0du6c27u4ee3uff0d1uff0c2uff0d3u03bau03b1u03c1u03b2u03bfu03beu03b1u03bcu03b9u03b4u03afu03bfu03c5u548cu03b4u03b9u03cbu03b4u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bd In such salt.It is also revealed that a pharmaceutical composition includes at least one crystalline form of N-(4-(2-amino-4-_lambda_lambda_phi_) -3-3. 1-(4-phiphi-4-ethoxy-1---(4-phiphiphi9595959595959595959595__delta_ -4-_lambda Zeta_) -3-____lambda-4-ethoxy-1-(4-___lambda) -2-oxo-1,____delta_-2-3-kappa___is used in the treatment of cancer and other proliferative diseases and/or processes to prepare crystalline forms of N-(4-(2-um) NO - 3 - 4 -u03c7u03bbu03c9u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bdu03c5u03bbu03bfu03beu03c5uff09-3-u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09-4-u4e59u6c27u57fa-1-uff084-u03c6u03b8u03bfu03c1u03bfu03c6u03b1u03b9u03bdu03c5u03bbuff09-2-u6c27u4ee3-1uff0c2-u03b4u03b9u03cbu03b4u03c1u03bfu03c0u03c5u03c1u03b9u03b4u03b9u03bd- 3 -u8fd9u03bau03b1u03c1u03b2u03bfu03beu03b1u03bcu03b9u03b4u03afu03bfu03c5u548cu76d0u3002

机译：u76d0 u548c u7ed3 u6676 u5f62 u5f0f uff0c u63ed u793a u4e86N uff0d uff08d uff0d uff082 uff0d u6c28 u57fa uff0d4 uff0d u03c5 u03bb u03b u03bb u03c9 u03c1 u03bf u03c0 u03c5 u03c1 u03b9 u03b4 u03b9 u03bd uff09- 3- u03c6 u03b8 u03bf u03c1 u03bf u03c6 u03b1 u03b6 u03b1 u03b1 uff09-4- u4e59 u6c27 u57fa-1- uff084- u03c6 u03b8 u03bf u03b1 u03bd u03c6 u03b1 u03b9 u03bd u03c5 u03bb uff09 uff0d2 uff0d u6c27 4 uff0c2 uff0d3 u03ba u03b1 u03c1 u03b2 u03bf u03be u03b1 u03bc u03b9 u03b4 u03af u03bf u03c5 u548c u03b4 u03b9 u03cb u03bc u03bc u03bc u03bc在该盐中还揭示了药物组合物包含至少一种结晶形式的N-（4-（2-氨基-4-_lambda_lambda_phi_）-3-3。1-（4 -phiphi-4-ethoxy-1 ---（4-phiphiphi95959595959595959595 95 ____ delta_ -4-_lambda Zeta_）-3 -____ lambda-4-ethoxy-1-（4 -__ lambda）-2-oxo-1， ____ delta_-2-3-kappa ___用于治疗癌症和其他增生性疾病和/或制备N-（4-（2-um）NO-3-4- u03c7 u03bb u03c9 u03c1 u03bf u03c0 u03c5 u03c1 u03b9 u03b4 u03b9 u03bd u03c5 u03bb u03bf u03be u03c5 uff09-3- u03c6 u03b8 u03bfuu03c1 u03bf u03b9 u03c5 u03bb uff09-4- u4e59 u6c27 u57fa-1- uff084- u03c6 u03b8 u03bf u03c1 u03bf u03c6 u03b1 u03b9 u03bd u03c5 u03bb uff09-2- u6c27 u4ee3-1 uff0c2- u03b4 u03b9 u03cb u03b4 u03c1 u03bf u03c0 u03c5 u03c1 u03b9 u03b4 u03b9 u03bd- 3- u8fd9 u03ba u03b1 u03b1 u03b1 u03b1 u03b1 u03bc u03b9 u03b4 u03af u03bf u03c5 u548c u76d0 u3002

著录项

公开/公告号CY1116335T1

专利类型
公开/公告日2017-02-08

原文格式PDF
申请/专利权人 BRISTOL-MYERS SQUIBB COMPANY;
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申请/专利号CY201511000301T
发明设计人 BINDRA DILBIR S;GOKHALE MADHUSHREE YESHWANT;NUNES CLETUS JOHN;ROSSO VICTOR W;SCHROEDER GRETCHEN M;THAKUR AJIT B;YIN XIAOTIAN;
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申请日2015-03-26
分类号C07D213/82;A61K31/444;A61P35;
国家 CY
入库时间 2022-08-21 13:39:34