(R) - apy lambda a lambda KY lambda amino derivatives and those containing these drugs

摘要

The invention relates to the selected (R) - alpha, rho, Lama, alpha, lambda, and a derivative. These compounds showed an unexpectedly powerful inhibitory effect___________96 The compounds of the invention do not have absolutely no CXCL8 inhibitory activity.These compounds are useful in the treatment of diseases alpha kappa kappa_dependent activation of neutrophil and monocyte apoptosis The score of complement C5a.Specifically, the compounds of the present invention are useful in the treatment of sepsis, psoriasis, rheumatoid arthritis, ulcerative colitis, and acute traumatic syndrome. Let US respiratory distress, idiopathic fibrosis, prevention and treatment of__and injury-induced ischemia and_ (2).