The main purpose of the present invention is to provide a factor for the treatment of inflammatory bowel diseases.The present invention relates to a factor containing a derivative of epsilon_epsilon p_kappa_kappa lambda_kappa represented by A for the treatment of inflammatory bowel diseases. In the general formula (1) or pharmaceutically acceptable salts as active___alpha____.In R1 and R2 are the same or different, each representing an optional_pi_kappa alpha____alpha_________ This is the hydrogen atom of p_gamma_or alpha lambda kappa_R5, the alkyl group or alpha lambda gamma_.Y represents the human or_o.A is nr6, R6 is the hydrogen atom, alpha lambda kappa lambda Alleles and so on.D represents alpha lambda_or alpha lambda_lambda_is an optional___hydroxyl group; _; is a simple link;_____ O, S, Q represent. And carboxyl groups, alpha lambda.
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