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Antimicrobial preservatives to obtain multi-dose formulations using beta-cyclodextrins for liquid dosage forms
Antimicrobial preservatives to obtain multi-dose formulations using beta-cyclodextrins for liquid dosage forms
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机译:使用β-环糊精制成液体剂型的抗微生物防腐剂以获得多剂量制剂
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摘要
The present invention is directed to pharmaceutical compositions containing a therapeutically effective amount of an Active Pharmaceutical Ingredient (API), a pharmaceutically acceptable cyclodextrin and a pharmaceutically acceptable preservative. The invention is also directed to pharmaceutical compositions of the compounds of Formula (I) wherein R2 is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl and a pharmaceutically acceptable cyclodextrin and preservative. Formula (I): In particular, the invention is directed to pharmaceutical compositions of the compound of Formula 1a, and a pharmaceutically acceptable cyclodextrin and a preservative.
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