USE OF NON-GLYCOSYLATED APOLIPOPROTEIN A-IV PROTEIN FOR TREATING TYPE 2 DIABETES MELLITUS

摘要

Described is the use of a non-glycosylated apolipoprotein A-IV protein for treating type two diabetes mellitus in a subject in need thereof, wherein the non-glycosylated apolipoprotein A-IV is produced by a protein expression system and has the amino acid sequence SEQ ID NO. 4, wherein X₁ is G, A or V, X₂ is E or K, X₃ is T or S, and X₄ is Q or H. Also described is the use of a pharmaceutical composition comprising said protein for treating diabetes mellitus in a subject in need thereof.