TREATMENT OF THE CHRONIC DISEASE OF THE KIDNEYS AND OTHER DAMAGE OF THE KIDNEY FUNCTION BY MEANS OF THE GDF15 MODULATOR

摘要

The invention relates to methods and compositions for treating an individual with a renal disorder, such as chronic kidney disease (CKD), terminal renal failure, diabetes, insulin resistance, renal hypertrophy, renal hypotrophy, polycystic kidney disease, proteinuria, hyperglycemia, hyperuricemia , gout, kidney stones, hypertension or hypertensive nephropathy, dyslipidemia, anemia and / or reduced erythropoietin production, iron deficiency or hyperfiltration. Methods and compositions use or contain a composition that reduces or inhibits the activity of GDF15.