The invention discloses a method for isolating a biopolymer from gossypium herbaceum seeds and formulating bionanoparticles loaded with Zidovudine and using the gossypium herbaceum biopolymer as a nanocarrier. The biopolymer from gossypium herbaceum isolated by simplified and economical process and subjected for physical and spectral studies, which includes IR, NMR, DSC and UV spectroscopy which confirms its polymeric nature. The biopolymer was devoid of acute toxicity. The different Zidovudine nanoparticles were prepared using nanocarriers and other coprocessing agents and evaluated for its retardabiIity, in vitro release studies, dispersibility and particle size determination. The results suggests that the nanocarrlers show promising retardability and the formulation is feasible for for lung specificity.
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