PROCESS FOR THE PREPARATION OF(4R,12AS)-9-{(2,4- DIFLUOROPHENYL)METHYLCARBAMOYL}-4-METHYL-6,8-DIOXO-3,4,6,8,12,12A-HEXAHYDRO-2H-PYRIDO1',2':4,5 PYRAZINO2,1-B1,3OXAZIN-7-OL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

摘要

The present invention relates to process for the preparation of (4R,12aS)-9-{[(2,4-difluorophenyl)methyl]carbamoy [r,2,:4s5]pyrazino[2,l-b][l,3]pxazin-7-ol represented by the following structural formula-1 and pharmaceutical acceptable salts thereof.