COMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS,

摘要

pOne aspect of the present invention relates to isoxazoline derivatives that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising an isoxazoline derivative of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer./p[WO2006009869A1]